Dipeptidyl peptidase 9 enzymatic activity influences the expression of neonatal metabolic genes.

@article{Chen2016DipeptidylP9,
  title={Dipeptidyl peptidase 9 enzymatic activity influences the expression of neonatal metabolic genes.},
  author={Yiqian Chen and Margaret G. Gall and Hui Emma Zhang and Fiona M. Keane and Geoffrey W McCaughan and Denise Ming Tse Yu and Mark D. Gorrell},
  journal={Experimental cell research},
  year={2016},
  volume={342 1},
  pages={
          72-82
        }
}
The success of dipeptidyl peptidase 4 (DPP4) inhibition as a type 2 diabetes therapy has encouraged deeper examination of the post-proline DPP enzymes. DPP9 has been implicated in immunoregulation, disease pathogenesis and metabolism. The DPP9 enzyme-inactive (Dpp9 gene knock-in; Dpp9 gki) mouse displays neonatal lethality, suggesting that DPP9 enzyme activity is essential in neonatal development. Here we present gene expression patterns in these Dpp9 gki neonatal mice. Taqman PCR arrays and… 
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