Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72

@inproceedings{Mann2013DipeptideRP,
  title={Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72},
  author={David M A Mann and Sara J Rollinson and Andrew C. Robinson and Janis Bennion Callister and Jennifer C. Thompson and Julie S. Snowden and Tania F. Gendron and Leonard Petrucelli and Masami Masuda-Suzukake and Masato Hasegawa and Yvonne S. Davidson and Stuart M. Pickering-Brown},
  booktitle={Acta neuropathologica communications},
  year={2013}
}
BACKGROUND Cases of Frontotemporal Lobar Degeneration (FTLD) and Motor Neurone Disease (MND) associated with expansions in C9ORF72 gene are characterised pathologically by the presence of TDP-43 negative, but p62 positive, inclusions in granule cells of the cerebellum and in cells of dentate gyrus and area CA4 of the hippocampus. RESULTS We screened 84 cases of pathologically confirmed FTLD and 23 cases of MND for the presence of p62 positive inclusions in these three brain regions, and… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
62 Citations
48 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 62 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 48 references

C 9 orf 72 repeat expansions are a rare genetic cause of Parkinsonism

  • S Lesage, I LeBer, +10 authors A Brice
  • Brain
  • 2013

Similar Papers

Loading similar papers…