Dioxin exposure and porcine reproductive hormonal activity.

  title={Dioxin exposure and porcine reproductive hormonal activity.},
  author={Ewa Łucja Gregoraszczuk},
  journal={Cadernos de saude publica},
  volume={18 2},
To characterize the action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during both the follicular and luteal phases of the ovarian cycle, the direct effect of TCDD was investigated in vitro using a system of primary monolayer cell culture. Granulosa and theca cells were collected from the preovulatory follicles and cultured as a co-culture, thus resembling follicles in vivo. Luteal cells were isolated from the corpora lutea collected during the midluteal phase. In both cases cells were… CONTINUE READING