Dioxin Exposure, from Infancy through Puberty, Produces Endocrine Disruption and Affects Human Semen Quality

  title={Dioxin Exposure, from Infancy through Puberty, Produces Endocrine Disruption and Affects Human Semen Quality},
  author={Paolo Mocarelli and Pier Mario Gerthoux and Donald J. Patterson and S Milani and Giuseppe Limonta and Maria Bertona and Stefano G. Signorini and Pierluigi Tramacere and Laura Colombo and Carla Crespi and Paolo Brambilla and Cecilia Sarto and Vittorio Carreri and Eric J. Sampson and Wayman E. Turner and Larry L Grandjean Needham},
  booktitle={Environmental health perspectives},
BACKGROUND Environmental toxicants are allegedly involved in decreasing semen quality in recent decades; however, definitive proof is not yet available. In 1976 an accident exposed residents in Seveso, Italy, to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). OBJECTIVE The purpose of this study was to investigate reproductive hormones and sperm quality in exposed males. METHODS We studied 135 males exposed to TCDD at three age groups, infancy/prepuberty (1-9 years), puberty (10-17 years), and… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 82 extracted citations

Overview of air pollution and endocrine disorders

International journal of general medicine • 2018
View 1 Excerpt


Publications referenced by this paper.
Showing 1-10 of 42 references

High - resolution gaschromatography / high - resolution mass spectrometric analysis of human serum on a whole weight and lipid basis for 2 , 3 , 7 , 8tetrachlorodibenzopdioxin

DG Patterson, L Hampton, +3 authors L Alexander
Anal Chem • 1987
View 3 Excerpts
Highly Influenced

Health effects of dioxin exposure: a 20-year mortality study.

American journal of epidemiology • 2001
View 8 Excerpts
Highly Influenced

androgen during postnatal development in the mouse

N Jorgensen, AG Andersen, +3 authors JH Petersen
Hum Reprod • 2001
View 4 Excerpts
Highly Influenced

Developmental male reproductive toxicology of 2 , 3 , 7 , 8tetrachlorodibenzopdioxin ( TCDD ) and PCBs

BL Roman, RE Peterson
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…