Dioxin Exposure, from Infancy through Puberty, Produces Endocrine Disruption and Affects Human Semen Quality

@inproceedings{Mocarelli2008DioxinEF,
  title={Dioxin Exposure, from Infancy through Puberty, Produces Endocrine Disruption and Affects Human Semen Quality},
  author={Paolo Mocarelli and Pier Mario Gerthoux and Donald J. Patterson and S Milani and Giuseppe Limonta and Maria Bertona and Stefano G. Signorini and Pierluigi Tramacere and Laura Colombo and Carla Crespi and Paolo Brambilla and Cecilia Sarto and Vittorio Carreri and Eric J. Sampson and Wayman E. Turner and Larry L Grandjean Needham},
  booktitle={Environmental health perspectives},
  year={2008}
}
BACKGROUND Environmental toxicants are allegedly involved in decreasing semen quality in recent decades; however, definitive proof is not yet available. In 1976 an accident exposed residents in Seveso, Italy, to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). OBJECTIVE The purpose of this study was to investigate reproductive hormones and sperm quality in exposed males. METHODS We studied 135 males exposed to TCDD at three age groups, infancy/prepuberty (1-9 years), puberty (10-17 years), and… CONTINUE READING

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