Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues.

@article{Uemura2010DiosgeninPI,
  title={Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues.},
  author={Taku Uemura and Shizuka Hirai and Noriko Mizoguchi and Tsuyoshi Goto and Joo Yong Lee and Keiko Taketani and Yuki Nakano and Jinji Shono and Shohei Hoshino and Nobuaki Tsuge and Toshihiko Narukami and Nobuyuki Takahashi and Teruo Kawada},
  journal={Molecular nutrition & food research},
  year={2010},
  volume={54 11},
  pages={1596-608}
}
In obesity, adipocyte hypertrophy and chronic inflammation in adipose tissues cause insulin resistance and type-2 diabetes. Trigonella foenum-graecum (fenugreek) can ameliorate hyperglycemia and diabetes. However, the effects of fenugreek on adipocyte size and inflammation in adipose tissues have not been demonstrated. In this study, we determined the effects of fenugreek on adipocyte size and inflammation in adipose tissues in diabetic obese KK-Ay mice, and identified the active substance in… CONTINUE READING

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