Diosgenin-induced biliary cholesterol secretion in mice requires Abcg8.

Abstract

The plant sterol diosgenin has been shown to stimulate biliary cholesterol secretion in mice without affecting the expression of the adenosine triphosphate-binding cassette transporter heterodimer Abcg5/g8. The aim of this study was to investigate the mechanism of diosgenin-induced cholesterol hypersecretion and to identify the genes involved. Surprisingly… (More)

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Cite this paper

@article{Kosters2005DiosgenininducedBC, title={Diosgenin-induced biliary cholesterol secretion in mice requires Abcg8.}, author={Astrid Kosters and Raoul Frijters and Cindy Kunne and Edwin Vink and Marit S Schneiders and Frank G Schaap and Catherina P Nibbering and Shailendra B Patel and Albert K. Groen}, journal={Hepatology}, year={2005}, volume={41 1}, pages={141-50} }