Diminished plasma oxytocin in schizophrenic patients with neuroendocrine dysfunction and emotional deficits.

@article{Goldman2008DiminishedPO,
  title={Diminished plasma oxytocin in schizophrenic patients with neuroendocrine dysfunction and emotional deficits.},
  author={Morris B. Goldman and Megan Marlow-O'Connor and Ivan Omar Olguin Torres and Cameron S. Carter},
  journal={Schizophrenia research},
  year={2008},
  volume={98 1-3},
  pages={247-55}
}
Polydipsic hyponatremic schizophrenic patients (PHS) exhibit enhanced plasma arginine vasopressin (pAVP) and hypothalamic pituitary adrenal (HPA) axis responses to stress that appear attributable to anterior hippocampal dysfunction. Neuroanatomic and electrophysiologic studies indicate oxytocin activity in PHS patients should also be affected. Furthermore, oxytocin normally diminishes HPA responses to stress and facilitates cognitive and behavioral functions impaired in schizophrenia… CONTINUE READING