Dimethylthetin can substitute for glycine betaine as an osmoprotectant molecule for Escherichia coli.
@article{Chambers1987DimethylthetinCS, title={Dimethylthetin can substitute for glycine betaine as an osmoprotectant molecule for Escherichia coli.}, author={S. Chambers and C. Kunin and D. Miller and A. Hamada}, journal={Journal of bacteriology}, year={1987}, volume={169 10}, pages={ 4845-7 } }
Glycine betaine is believed to be the most active naturally occurring osmoprotectant molecule for Escherichia coli and other bacteria. It is a dipolar ion possessing a quaternary ammonimum group and a carboxylic acid group. To examine the molecular requirements for osmoprotective activity, dimethylthetin was compared with glycine betaine. Dimethylthetin is identical to glycine betaine except for substitution of dimethyl sulfonium for the quaternary nitrogen group. Dimethylthetin was found to be… CONTINUE READING
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References
SHOWING 1-10 OF 11 REFERENCES
Isolation of glycine betaine and proline betaine from human urine. Assessment of their role as osmoprotective agents for bacteria and the kidney.
- Chemistry, Medicine
- The Journal of clinical investigation
- 1987
- 83
- PDF
Glycine betaine transport in Escherichia coli: osmotic modulation.
- Biology, Medicine
- Journal of bacteriology
- 1985
- 220
- PDF
Betaine is the main compatible solute of halophilic eubacteria.
- Biology, Medicine
- Journal of bacteriology
- 1984
- 180
- PDF
The osmoprotective properties of urine for bacteria: the protective effect of betaine and human urine against low pH and high concentrations of electrolytes, sugars, and urea.
- Chemistry, Medicine
- The Journal of infectious diseases
- 1985
- 74
Influence of osmolarity of the growth medium on the outer membrane protein pattern of Escherichia coli.
- Biology, Medicine
- Journal of bacteriology
- 1977
- 220
- PDF
Identification of the structural proteins of an ATP-driven potassium transport system in Escherichia coli.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1978
- 57
- PDF
Predominant osmotically active organic solutes in rat and rabbit renal medullas.
- Medicine, Chemistry
- The Journal of biological chemistry
- 1986
- 357
- PDF