Dimethylthetin can substitute for glycine betaine as an osmoprotectant molecule for Escherichia coli.

  title={Dimethylthetin can substitute for glycine betaine as an osmoprotectant molecule for Escherichia coli.},
  author={S. Chambers and C. Kunin and D. Miller and A. Hamada},
  journal={Journal of bacteriology},
  volume={169 10},
  • S. Chambers, C. Kunin, +1 author A. Hamada
  • Published 1987
  • Biology, Medicine
  • Journal of bacteriology
  • Glycine betaine is believed to be the most active naturally occurring osmoprotectant molecule for Escherichia coli and other bacteria. It is a dipolar ion possessing a quaternary ammonimum group and a carboxylic acid group. To examine the molecular requirements for osmoprotective activity, dimethylthetin was compared with glycine betaine. Dimethylthetin is identical to glycine betaine except for substitution of dimethyl sulfonium for the quaternary nitrogen group. Dimethylthetin was found to be… CONTINUE READING
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