Dimethylarginines in chronic renal failure.

  title={Dimethylarginines in chronic renal failure.},
  author={N Wahbi and R. Neil Dalton and Cheryl Turner and Mark S. Denton and Ian Abbs and Ramasamyiyer Swaminathan},
  journal={Journal of clinical pathology},
  volume={54 6},
BACKGROUND Nitric oxide (NO) is a potent chemical mediator involved in many functions. In vivo production of NO is thought to be regulated by endogenous analogues of L-arginine: asymmetric dimethylarginine (ADMA). AIM To examine the effect of renal function and dialysis on the serum concentrations of ADMA and symmetric dimethylarginine (SDMA). METHODS Blood samples were obtained from nine healthy subjects, patients with renal failure before (n = 17) and after haemodialysis (n = 9), nine… CONTINUE READING