Dimeric heat shock protein 40 binds radial spokes for generating coupled power strokes and recovery strokes of 9 + 2 flagella

@article{Yang2008DimericHS,
  title={Dimeric heat shock protein 40 binds radial spokes for generating coupled power strokes and recovery strokes of 9 + 2 flagella},
  author={Chun Ho Yang and Heather A. Owen and Pinfen Yang},
  journal={The Journal of Cell Biology},
  year={2008},
  volume={180},
  pages={403 - 415}
}
T-shape radial spokes regulate flagellar beating. However, the precise function and molecular mechanism of these spokes remain unclear. Interestingly, Chlamydomonas reinhardtii flagella lacking a dimeric heat shock protein (HSP) 40 at the spokehead-spokestalk juncture appear normal in length and composition but twitch actively while cells jiggle without procession, resembling a central pair (CP) mutant. HSP40(-) cells begin swimming upon electroporation with recombinant HSP40. Surprisingly, the… CONTINUE READING

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Mentioned Connections BETA
CiliaNo subtypeFlagella
This enables 9 + 2 cilia and flagella to bend and switch to generate alternate power strokes and recovery strokes .
CiliaNo subtypeFlagella
This enables 9 + 2 cilia and flagella to bend and switch to generate alternate power strokes and recovery strokes .
FlagellaNo subtypeCilia
This enables 9 + 2 cilia and flagella to bend and switch to generate alternate power strokes and recovery strokes .
CiliaSibling in is aFlagella
This enables 9 + 2 cilia and flagella to bend and switch to generate alternate power strokes and recovery strokes .
FlagellaSibling in is aCilia
This enables 9 + 2 cilia and flagella to bend and switch to generate alternate power strokes and recovery strokes .
FlagellaNo subtypeCilia
This enables 9 + 2 cilia and flagella to bend and switch to generate alternate power strokes and recovery strokes .
This enables 9 + 2 cilia and flagella to bend and switch to generate alternate power strokes and recovery strokes .
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