Dimeric binding of the mouse germ cell nuclear factor.

@article{Borgmeyer1997DimericBO,
  title={Dimeric binding of the mouse germ cell nuclear factor.},
  author={Uwe Borgmeyer},
  journal={European journal of biochemistry},
  year={1997},
  volume={244 1},
  pages={120-7}
}
The mouse germ cell nuclear factor (GCNF), a member of the nuclear receptor superfamily, is highly expressed during spermatogenesis, oogenesis, and during neuronal embryonic differentiation. The in vitro translated receptor binds autonomously to the direct repeat of the sequence 5'-AGGTCA-3'. To gain insights into the determinants necessary for DNA binding, I have generated truncated GCNF molecules by introducing carboxy-terminal deletions into expression constructs. An electrophoretic mobility… CONTINUE READING
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