Dimensionless analysis of swelling of hydrophilic glassy polymers with subsequent drug release from relaxing structures.

@article{Brazel1999DimensionlessAO,
  title={Dimensionless analysis of swelling of hydrophilic glassy polymers with subsequent drug release from relaxing structures.},
  author={Christopher S. Brazel and Nicholas A Peppas},
  journal={Biomaterials},
  year={1999},
  volume={20 8},
  pages={
          721-32
        }
}
  • Christopher S. Brazel, Nicholas A Peppas
  • Published 1999
  • Materials Science, Medicine
  • Biomaterials
  • Two dimensionless parameters, the diffusional Deborah number, De, and the swelling interface number, Sw, were used as indicators of solvent and solute transport behavior in swellable hydrogel systems. Polymer relaxation and concentration-dependent diffusion led to dynamically swelling polymers which displayed Fickian, Case II, or anomalous transport behavior. Experimental systems studied included crosslinked samples of poly(vinyl alcohol), designated PVA, and poly(2-hydroxyethyl methacrylate-co… CONTINUE READING

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    • Christopher S. Brazel, Nicholas A Peppas
    • Chemistry, Medicine
    • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
    • 2000

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