Dimenhydrinate Abuse among Adolescentsa

@article{Gardner1993DimenhydrinateAA,
  title={Dimenhydrinate Abuse among Adolescentsa},
  author={David M Gardner and Stan Kutcher},
  journal={The Canadian Journal of Psychiatry},
  year={1993},
  volume={38},
  pages={113 - 116}
}
Dimenhydrinate may be a relatively common yet unrecognized substance of abuse among adolescents. Abuse of this drug may present as a psychiatric syndrome, particularly depression. Three cases are presented which illustrate this relationship. A review of the literature is presented and suggestions are made for identifying adolescents who abuse dimenhydrinate. 
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TLDR
Molecular mechanics and dynamic simulations showed that AM1 derived parameters, together with MNDO ESP fitted atomic charges, predicted the X-ray structure of a number of representative [1,4]-benzodiazepines within 0.01 A, 0.8 degree, and 5 degrees, from observed bond lengths, bond angles, and bond torsions, respectively.
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