Diluted bitumen causes deformities and molecular responses indicative of oxidative stress in Japanese medaka embryos.

@article{Madison2015DilutedBC,
  title={Diluted bitumen causes deformities and molecular responses indicative of oxidative stress in Japanese medaka embryos.},
  author={Barry N. Madison and Peter V Hodson and Valerie S Langlois},
  journal={Aquatic toxicology},
  year={2015},
  volume={165},
  pages={222-30}
}
This study characterized the toxicity and physiological effects of unweathered diluted bitumen (Access Western Blend dilbit; AWB) to fish. Embryos of Japanese medaka (Oryzias latipes) were exposed for 17 days to dilutions of physically-dispersed (water accommodated fraction; WAF) and chemically-dispersed (chemically-enhanced WAF; CEWAF) dilbit. AWB dilbit exposure was not lethal to medaka, but resulted in a high prevalence of blue sac disease (BSD), impaired development, and abnormal or un… CONTINUE READING
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