Dilute Russell's viper venom and activated partial thromboplastin time in lupus anticoagulant diagnosis: is mixing essential?

@article{Chandrashekar2016DiluteRV,
  title={Dilute Russell's viper venom and activated partial thromboplastin time in lupus anticoagulant diagnosis: is mixing essential?},
  author={Vani Chandrashekar},
  journal={Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis},
  year={2016},
  volume={27 4},
  pages={408-11}
}
Dilute Russell's viper venom (DRVV) testing and activated partial thromboplastin time (APTT) have been effectively used in combination for lupus anticoagulant testing. The purpose of our study was to evaluate the role of mixing in activated partial thromboplastin and dilute Russell's viper venom testing for evaluation of lupus anticoagulants. Citrated blood from patients who were not on oral anticoagulant therapy was studied. Mixing study with 1 : 1 normal plasma for elevated APTT and also few… CONTINUE READING
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Laboratory testing for the lupus anticoagulant. Approved guideline – first edition. CLSI document H60

MR Ledford-Kraemer, GW Moore, +3 authors T Exner
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