Dilemmas in diagnosis and management of cephalosporin-resistant Streptococcus pneumoniae meningitis.

@article{Friedland1993DilemmasID,
  title={Dilemmas in diagnosis and management of cephalosporin-resistant Streptococcus pneumoniae meningitis.},
  author={Ian R. Friedland and S J Shelton and Mar{\'i}a M Par{\'i}s and S B Rinderknecht and S L Ehrett and Karen K Krisher and George H Mccracken},
  journal={The Pediatric infectious disease journal},
  year={1993},
  volume={12 3},
  pages={196-200}
}
We recently managed an infant with meningitis caused by Streptococcus pneumoniae in whom ceftriaxone failed to sterilize the cerebrospinal fluid after 6 days of therapy. This strain, which had a penicillin minimal inhibitory concentration (MIC) of 2 micrograms/ml, appeared susceptible to ceftriaxone (MIC < 0.5 micrograms/ml) when evaluated by a commercial MIC panel (Microtech Medical Systems, Inc., Aurora, CO) but was found to have a ceftriaxone MIC of 4 micrograms/ml when evaluated by… CONTINUE READING

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Clinical isolates of Streptococcus pneumoniae that exhibit tolerance of vancomycin.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2001

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