Dilatory responses to estrogenic compounds in small femoral arteries of male and female estrogen receptor-beta knockout mice.

@article{Cruz2006DilatoryRT,
  title={Dilatory responses to estrogenic compounds in small femoral arteries of male and female estrogen receptor-beta knockout mice.},
  author={Mar{\'i}a Natalia Cruz and G Sutherland Douglas and Jan-{\AA}ke Gustafsson and Lucilla Poston and Karolina R. Kublickiene},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2006},
  volume={290 2},
  pages={
          H823-9
        }
}
The objectives of this study were to determine whether acute dilatory responses to estrogen receptor agonists are altered in isolated arteries from estrogen receptor beta-deficient mice (beta-ERKO) and to gain insight into the role of nitric oxide (NO) in these responses. Femoral arteries (approximately 250 microm) from male and female beta-ERKO mice and wild-type (WT) littermates (26 female, 13 in each group; and 24 male, 12 in each group) were mounted on a Multi-Myograph. Concentration… CONTINUE READING

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