Diisopropylfluorophosphate inhibits choline efflux from the perfused rat hemidiaphragm.

Abstract

Acetylcholine (ACh) synthesis by motor nerve terminals requires an adequate supply of its precursor, choline. The results reported here show that diisopropylfluorophosphate (DFP), an acetylcholinesterase inhibitor commonly used in ACh release studies, reduces the rate of endogenous choline efflux from the perfused rat hemidiaphragm. Perfusion of the… (More)

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@article{Millington1985DiisopropylfluorophosphateIC, title={Diisopropylfluorophosphate inhibits choline efflux from the perfused rat hemidiaphragm.}, author={William R. Millington and Andrew C. Myers and G G Bierkamper}, journal={European journal of pharmacology}, year={1985}, volume={115 1}, pages={37-44} }