Diisocyanates, occupational asthma and IgE antibody: implications for hazard characterization

@article{Kimber2014DiisocyanatesOA,
  title={Diisocyanates, occupational asthma and IgE antibody: implications for hazard characterization},
  author={I. Kimber and R. Dearman and D. Basketter},
  journal={Journal of Applied Toxicology},
  year={2014},
  volume={34},
  pages={1073 - 1077}
}
  • I. Kimber, R. Dearman, D. Basketter
  • Published 2014
  • Medicine
  • Journal of Applied Toxicology
  • Sensitization of the respiratory tract by chemicals resulting in rhinitis and asthma is an important occupational health issue. Occupational asthma is associated with significant morbidity and can be fatal. Tests for the identification and characterization of chemicals with the potential to cause sensitization of the respiratory tract are lacking. In spite of sustained interest there are no validated or widely accepted methods available, and this presents toxicologists with a considerable… CONTINUE READING
    17 Citations
    Thresholds in chemical respiratory sensitisation.
    • 24
    • PDF
    Fragrance sensitisers: Is inhalation an allergy risk?
    • 10
    Behaviour of chemical respiratory allergens in novel predictive methods for skin sensitisation.
    • 8
    How to assess respiratory sensitization of low molecular weight chemicals?
    • J. Arts
    • Medicine
    • International journal of hygiene and environmental health
    • 2020
    Fragrance inhalation and adverse health effects: The question of causation
    • 4
    Anti‐hapten antibodies in response to skin sensitization
    • 6
    • PDF
    Azodicarbonamide (ADCA): A reconsideration of classification as a respiratory sensitiser.
    • 3
    • Highly Influenced
    Neuro-immune interactions in chemical-induced airway hyperreactivity
    • 25
    • PDF

    References

    SHOWING 1-10 OF 66 REFERENCES
    Chemical allergy: translating biology into hazard characterization.
    • 116
    • PDF
    Chemical respiratory allergy, IgE and the relevance of predictive test methods: a commentary
    • 25
    Chemical respiratory allergy: reverse engineering an adverse outcome pathway.
    • 45
    Pro/Con debate: is occupational asthma induced by isocyanates an immunoglobulin E‐mediated disease?
    • A. Wisnewski, M. Jones
    • Medicine
    • Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
    • 2010
    • 34
    Is occupational asthma to diisocyanates a non-IgE-mediated disease?
    • 78
    • Highly Influential
    Chemical allergy: considerations for the practical application of cytokine profiling.
    • R. Dearman, C. Betts, +4 authors I. Kimber
    • Biology, Medicine
    • Toxicological sciences : an official journal of the Society of Toxicology
    • 2003
    • 74
    • PDF
    Assessing the potential to induce respiratory hypersensitivity.
    • 57
    • PDF
    Respiratory sensitization and allergy: current research approaches and needs.
    • 81
    • PDF
    Specific serum antibodies against isocyanates: association with occupational asthma.
    • 204
    • Highly Influential