Dihydrotestosterone and the concept of 5α-reductase inhibition in human benign prostatic hyperplasia

@article{Bartsch2002DihydrotestosteroneAT,
  title={Dihydrotestosterone and the concept of 5$\alpha$-reductase inhibition in human benign prostatic hyperplasia},
  author={Georg Bartsch and Roger S. Rittmaster and Helmut Klocker},
  journal={World Journal of Urology},
  year={2002},
  volume={19},
  pages={413-425}
}
Abstract. The development of human benign prostatic hyperplasia (BPH) clearly requires a combination of testicular androgens and the ageing process. Although the role of androgens as the causative factor for human benign prostatic hyperplasia is debated, they undoubtedly play, at least, a permissive role. The principal prostatic androgen is dihydrotestosterone. Although not elevated in human benign prostatic hyperplasia, dihydrotestosterone levels in the prostate remain at a normal level with… 
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