Dihydropyridine calcium channel blockers and the progression of parkinsonism.

@article{Marras2012DihydropyridineCC,
  title={Dihydropyridine calcium channel blockers and the progression of parkinsonism.},
  author={Connie Marras and Andrea Gruneir and Paula Rochon and Xuesong Wang and Geoff Anderson and Jonathan Michael Brotchie and Chaim M. Bell and Susan S Fox and Peter C. Austin},
  journal={Annals of neurology},
  year={2012},
  volume={71 3},
  pages={362-9}
}
OBJECTIVE A study was undertaken to test the association between dihydropyridine calcium channel blocker use and the time to important milestones of disease progression among patients with parkinsonism. METHODS Data were obtained from Ontario's health care administrative databases. Within a cohort of hypertensive individuals older than 65 years who developed parkinsonism, we examined the effect of the length of exposure to less brain-penetrant dihydropyridines (amlodipine) and more brain… CONTINUE READING
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