Dihydropyridine calcium channel blockers and peripheral side effects

  title={Dihydropyridine calcium channel blockers and peripheral side effects},
  author={Alexander Sirker and C Missouris and G D MacGregor},
  journal={Journal of Human Hypertension},
A 56 year old Caucasian man was referred to our unit in 1994 with a 3-year history of elevated blood pressure. Six months previously he had been treated by his general practitioner with nifedipine tablets (Adalat Retard) 10 mg t.d.s. On examination, the mean supine blood pressure was 135/77 mm Hg. He had marked bilateral ankle swelling, hyperpigmentation of… CONTINUE READING