Dihydrolipoamide dehydrogenase and cAMP are associated with cadmium-mediated Leydig cell damage.

Abstract

Cadmium (Cd) directly inhibits testosterone production in Leydig cells, but its mechanism is still unclear. To further explore the signaling pathway of Cd-mediated toxicity to Leydig cells, various concentrations of Cd were cultured with R2C cells for 24h, and two-dimensional gel electrophoresis (2DE)-based proteomics profiling was used to analyze the… (More)
DOI: 10.1016/j.toxlet.2011.06.003

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@article{Zhang2011DihydrolipoamideDA, title={Dihydrolipoamide dehydrogenase and cAMP are associated with cadmium-mediated Leydig cell damage.}, author={Qihao Zhang and Ping Zou and Haichao Zhan and Minjing Zhang and Lei Zhang and Ren-Shan Ge and Yadong Huang}, journal={Toxicology letters}, year={2011}, volume={205 2}, pages={183-9} }