Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells

@article{Lu2008DihydroartemisininI,
  title={Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells},
  author={Yingying Lu and Tong-sheng Chen and Junle Qu and Wen-Liang Pan and Lei Sun and Xun-Bin Wei},
  journal={Journal of Biomedical Science},
  year={2008},
  volume={16},
  pages={16 - 16}
}
Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin, isolated from the traditional Chinese herb Artemisia annua, is recommended as the first-line anti-malarial drug with low toxicity. DHA has been shown to possess promising anticancer activities and induce cancer cell death through apoptotic pathways, although the molecular mechanisms are not well understood. In this study, cell counting kit (CCK-8) assay was employed to evaluate the survival of DHA-treated ASTC-a-1 cells. The… CONTINUE READING
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Evidence for the involvement of carbon-centered radical in the induction of apoptosis cell death by artemisinin compounds

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