Dihydroabietyl alcohol (Abitol®) A sensitizer in mascara

@article{Doomsgoossens1979DihydroabietylA,
  title={Dihydroabietyl alcohol (Abitol{\textregistered}) A sensitizer in mascara},
  author={A. Dooms‐goossens and H. Degreef and E Luytens},
  journal={Contact Dermatitis},
  year={1979},
  volume={5}
}
A nickel‐sensitized female patient developed a contact dermatitis reaction to her mascara that was maintained by her spectacle frames, which contained nickel. On patch testing, she reacted to dihydroabietyl alcohol (Abitol°). Which was present in her mascara, and hypoallergenic adhesive tape containing methyl abietate. There was also cross‐reactivity with colophony and abietic acid. 
Contact allergy due to colophony
TLDR
The sensitizing capacity of 7 commercial modified‐colophony products of different origins were studied experimentally in guinea pigs by means of a modified Freund's complete adjuvant (FCA) method, showing a weak sensitizing power, but a moderate to strong irritant effect.
Letter to the Editor
TLDR
It has recently learned that Tarpal tape contains abietic acid, and the allergic reaction is accounted for, and an eczematous reaction to "hypoallergenic" Tarpalan tape is explained.
Contact allergy to colophony
The sensitizing capacity of 15 commercial colophony products was studied experimentally in guinea pigs. The study included 8 French and 6 American colophony derivatives as well as French tall oil
Allergenic potential of abietic acid, colophony and pine resin‐HA
TLDR
The risk that the resin acids in tall oils would induce contact sensitivity to workers exposed to tall oil‐containing products like cutting fluids and cleansing agents is considered to be minimal.
Allergic contact dermatitis to a colophony derivative
5 patients developed acute allergic contact: dermatitis to a wood rosin present in the adhesive of tapes used to approximate the edges of incisions. The exposure history consistently included
Colophony, formaldehyde and mercury in mascaras
TLDR
Colophony was determined as methyl esters of the major resin acids after hydrolysis with ethanolic potassium hydroxide and formaldehyde was measured according to the European Commission Directive 90/207 /EEC, and mercury according to NIOSH method 6009 with cold vapour analysis.
Patch testing with colophony
TLDR
Routine patch testing with neutral components gives positive reactions at a 40% higher frequency than routine patchTesting with colophony (20%) (w/w in pet.).
Allergic contact dermatitis from a colophony derivative in a tape skin closure
TLDR
A 47-year-old man with psoriasis developed contact dermatitis on the hands 20 years ago andPatch tests were negative but he reacted to the adhesive tape, and histological picture consistent with a contact allergic reaction was shown.
Anaphylaxis from contact with carrot
TLDR
It is possible that X C leylandii is currently a significant source of al1ergic contact dermatitis in patients sensitive to colophony, and therefore promoted by garden centres and nurseries.
...
...

References

SHOWING 1-10 OF 10 REFERENCES
Allergic contact dermatitis to a salicylic acid plaster
TLDR
Two patients who developed allergic eczematous contact dermatitis to a salacid plaster used to treat plantar warts were subsequently shown to be allergic to dehydroabietic acid, a resin contained in the plaster.
A retrospective study of patch test results from 163 patients with stasis dermatitis or leg ulcers. II. Retesting of 50 patients.
TLDR
Retesting 50 patients with stasis dermatitis after a period of time (3-25 months) revealed significantly less positive patch test results (p less than 0.05), mainly due to elimination of the sensitization agents in the interim and testing with a less acute skin condition.
A retrospective study of Patch test results from 163 patients with stasis dermatitis or leg ulcers. I. Discussion of the Patch test results and the sensitization indices and determination of the relevancy of positive reactions.
Patch test results from 163 patients with leg ulcers and/or chronic venous insufficiency, tested with a modified ICDRG standard test battery and a pharmaceutical test series, are analyzed and
Multiple concomitant positive patch test reactions
TLDR
Thirty‐five patients who showed 90 one plus (+) patch test reactions to 28 patch test chemicals at Day 2 (D2) were retested to the chemicals at D7, suggesting that false positivePatch test reactions were common when more than one positive reaction was obtained by concomitant patch testing.
TECHNIQUE OF PATCH TESTING FOR COSMETIC ALLERGY *
TLDR
Whenever a number of patches are applied, the cosmetic that is under strongest suspciion and that may produce a reaction should be placed away from the other patches so that a strongly positive reaction will not spread and produce false reactions at adjacent sites.
Abietic acid and colophony
Monographs on fragrance raw materials - Hydroabietyl alcohol
  • Food and Cosmetic Toxicology
  • 1974
Abitol® Product information sheet
  • Hercules Powder Company
  • 1958
to a salicylic acid plas
  • 1978