Digoxin may provide protection against vasospasm in subarachnoid haemorrhage

Abstract

Vasospasm is a significant reason for poor clinical outcome in subarachnoid haemorrhage (SAH). One of the possible causes of vasospasm is attributed to the inhibition of Na+/K+-ATPase and increased intracellular calcium. Although digoxin, a cardiac glycoside (CG), inhibits the Na+/K+-ATPase, diverse and contradictory biological actions of CGs have also been… (More)
DOI: 10.1007/s00701-009-0391-5

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