Digitalis increases brain natriuretic peptide in patients with severe congestive heart failure.

@article{Tsutamoto1997DigitalisIB,
  title={Digitalis increases brain natriuretic peptide in patients with severe congestive heart failure.},
  author={Takayoshi Tsutamoto and Atsuyuki Wada and Keiko Maeda and Takashi Hisanaga and D Fukai and Yuta Maeda and Masato Ohnishi and Naoko Mabuchi and Masahiko Kinoshita},
  journal={American heart journal},
  year={1997},
  volume={134 5 Pt 1},
  pages={910-6}
}
Ouabain can cause increased secretion of atrial natriuretic peptide (ANP) from atrial cardiocyte culture, but the effects of digitalis in a therapeutic range on the secretion of cardiac natriuretic peptide including ANP and brain natriuretic peptide (BNP), mainly from the ventricle, in patients with congestive heart failure remain to be investigated. Therefore we studied the acute effects of intravenous infusion of a relatively low dose of digitalis or placebo on hemodynamics and neurohumoral… CONTINUE READING
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