Digital ion trap mass spectrometer for probing the structure of biological macromolecules by gas phase X-ray scattering.

@article{McCullough2009DigitalIT,
  title={Digital ion trap mass spectrometer for probing the structure of biological macromolecules by gas phase X-ray scattering.},
  author={Bryan J. McCullough and Andrew Lee Entwistle and Ikuo Konishi and Steven G Buffey and S Samar Hasnain and Francesco L. Brancia and J. G{\"u}nter Grossmann and Simon J. Gaskell},
  journal={Analytical chemistry},
  year={2009},
  volume={81 9},
  pages={3392-7}
}
Small-angle X-ray scattering is a technique for the characterization and structural analysis of a variety of materials including biological macromolecules and polymers. For the conformational analysis of proteins, the interaction between sample and X-rays is generally performed when the proteins are present in solution. Here a three-dimensional digital ion trap interfaced with a high intensity X-ray source is built to prove that X-ray scattering can be performed on ions isolated in gas-phase… CONTINUE READING

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Proceedings of the 55 th ASMS Conference on Mass Spectrometry

  • L. Ding, F. Brancia, R. Giles, S. Smirnov, E. Nickolaev
  • 2005

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