Digital gene expression tag profiling of bat digits provides robust candidates contributing to wing formation

@inproceedings{Wang2010DigitalGE,
  title={Digital gene expression tag profiling of bat digits provides robust candidates contributing to wing formation},
  author={Zhe Wang and Dong Dong and Binghua Ru and Rebecca L. Young and Naijian Han and Tingting Guo and Shuyi Zhang},
  booktitle={BMC Genomics},
  year={2010}
}
As the only truly flying mammals, bats use their unique wing - consisting of four elongated digits (digits II-V) connected by membranes - to power their flight. In addition to the elongated digits II-V, the forelimb contains one shorter digit (digit I) that is morphologically similar to the hindlimb digits. Here, we capitalized on the morphological variation among the bat forelimb digits to investigate the molecular mechanisms underlying digit elongation and wing formation. Using next… CONTINUE READING