Digital PCR: a powerful new tool for noninvasive prenatal diagnosis?

Abstract

Recent reports have indicated that digital PCR may be useful for the noninvasive detection of fetal aneuploidies by the analysis of cell-free DNA and RNA in maternal plasma or serum. In this review we provide an insight into the underlying technology and its previous application in the determination of the allelic frequencies of oncogenic alterations in… (More)
DOI: 10.1002/pd.2150

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