Digital Measurement of Myelofibrosis Associated Platelet Derived Growth Factor Receptor ß (PDGFR ß) Expression in Bone Marrow Biopsies

@article{Szeghalmy2013DigitalMO,
  title={Digital Measurement of Myelofibrosis Associated Platelet Derived Growth Factor Receptor {\ss} (PDGFR {\ss}) Expression in Bone Marrow Biopsies},
  author={Szilvia Szeghalmy and Judit Bedekovics and Gabor Mehes and Attila Fazekas},
  journal={CIT},
  year={2013},
  volume={21},
  pages={49-58}
}
In daily routine the reticulin silver staining is used on bone marrow biopsy samples as a gold standard for the characterization of myelofibrosis, however this method does not provide information about the prefibrotic stage. Recently a specific immunohistochemical method was introduced which may overcome these weaknesses of reticulin staining. Activated fibroblasts responsible for stromal proliferation are highlighted by increased PDGFR β expression, which can be presented by… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 28 REFERENCES

MAGLOGIANNIS , Advanced Cancer Cell Characterization and Quanti fi cation of Microscopy Images

D. A. T. HARPER O. HAMMER, P. D. RYAN
  • LNAI
  • 2012

Platelet derived growth factor receptor – an early marker of myelofibrosis

J. BEDEKOVICS, SZ. SZEGHALMY, A. FAZEKAS, G. MÉHES
  • Proc. of Modern sejtanalitikai módszerek: a VII. Magyar Sejtanalitikai Konferencia, 31 May–2 September,
  • 2012

A

T. C. CORNISH
  • M. DE MARZO, Tissue Microarrays inCancer Research.ModernMolecularBiology Applied Bioinformatics and Biostatistics in Cancer Research,
  • 2010
VIEW 1 EXCERPT

PANIGRAHI , Multilevel thresholding for image segmentation through a fast statistical recursive algorithm

J. ACHARYA S. ARORA, A. VERMA, K. PRASANTA
  • Pattern Recognition Letters
  • 2008

Biology and treatment of primary myelofibrosis.

  • Hematology. American Society of Hematology. Education Program
  • 2007

Similar Papers