Digital Mammography versus Digital Mammography Plus Tomosynthesis in Breast Cancer Screening: The Oslo Tomosynthesis Screening Trial.

@article{Skaane2019DigitalMV,
  title={Digital Mammography versus Digital Mammography Plus Tomosynthesis in Breast Cancer Screening: The Oslo Tomosynthesis Screening Trial.},
  author={P. Skaane and Andriy I. Bandos and L. Niklason and S. Sebu{\o}deg{\aa}rd and B. H. {\O}ster{\aa}s and R. Gullien and D. Gur and S. Hofvind},
  journal={Radiology},
  year={2019},
  volume={291 1},
  pages={
          23-30
        }
}
Background Digital breast tomosynthesis (DBT) is replacing digital mammography (DM) in the clinical workflow. Currently, there are limited prospective studies comparing the diagnostic accuracy of both examinations and the role of synthetic mammography (SM) and computer-aided detection (CAD). Purpose To compare the accuracy of DM versus DM + DBT in population-based breast cancer screening. Materials and Methods This prospective study, performed from November 2010 to December 2012, included 24… Expand
Digital Mammography versus Breast Tomosynthesis: Impact of Breast Density on Diagnostic Performance in Population-based Screening.
TLDR
Digital breast tomosynthesis enabled the detection of more cancers in all density and age groups compared with digital mammography, especially cancers classified as spiculated masses and architectural distortions. Expand
Multicenter Evaluation of Breast Cancer Screening with Digital Breast Tomosynthesis in Combination with Synthetic versus Digital Mammography.
TLDR
Breast cancer screening performance is maintained within benchmarks when synthetic mammography replaces digital mammography in digital breast tomosynthesis imaging. Expand
Interval and Consecutive Round Breast Cancer after Digital Breast Tomosynthesis and Synthetic 2D Mammography versus Standard 2D Digital Mammography in BreastScreen Norway.
TLDR
No differences in interval breast cancer rates or tumor characteristics were observed in Women screened with DBT and SM compared with women screened with DM, and higher rates of low-grade screen-detected tumors were observedIn the control group at consecutive screening. Expand
Breast cancer screening in women with and without implants: retrospective study comparing digital mammography to digital mammography combined with digital breast tomosynthesis
TLDR
Digital mammography with tomosynthesis improved recall rates, cancer detection rates, and positive predictive values for recall compared to digital mammography alone for women without implants and DM/DBT performance in women with implants trended towards similar improvements. Expand
Mammographic features and screening outcome in a randomized controlled trial comparing digital breast tomosynthesis and digital mammography.
TLDR
Spiculated mass was the dominant feature for breast cancer among women screened with DBT while calcifications was the most frequent feature for DM, while further studies exploring the clinical relevance of mammographic features visible particularly on DBT are warranted. Expand
Comparison of diagnostic performances in the evaluation of breast microcalcifications: synthetic mammography versus full-field digital mammography
Although several studies proved that SM could substitute for FFDM, the efficacy of SM in microcalcification evaluation remains controversial. To investigate the diagnostic performance of syntheticExpand
Comparing the diagnostic efficacy of digital breast tomosynthesis with full-field digital mammography using BI-RADS scoring
Background Mammography has been the mainstay for the detection of breast cancer over decades. It has gradually advanced from screen film to full-field digital mammography. Tomosynthesis has evolvedExpand
The cost-effectiveness of digital breast tomosynthesis in a population breast cancer screening program
TLDR
DBT has the potential to be cost-effective for screening all women when sensitivity is at least 90% at a maximum cost per screen of €80, and whether DBT could be used as an alternative to mammography for screened all women is highly dependent on the cost of DBT per screen. Expand
Two-view digital breast tomosynthesis versus digital mammography in a population-based breast cancer screening programme (To-Be): a randomised, controlled trial.
TLDR
It is indicated that digital breast tomosynthesis including synthetic 2D mammograms was not significantly different from standard digital mammography as a screening tool for the detection of breast cancer in a population-based screening programme. Expand
Breast Cancer Screening with Digital Breast Tomosynthesis: Are Initial Benefits Sustained?
TLDR
The benefits of reduced false-positive examinations and higher specificity with screening tomosynthesis were sustained after the first screening round at the individual level. Expand
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