Digit tip regrowth and differential gene expression in MRL/Mpj, DBA/2, and C57BL/6 mice.

@article{Chadwick2007DigitTR,
  title={Digit tip regrowth and differential gene expression in MRL/Mpj, DBA/2, and C57BL/6 mice.},
  author={Robert B. Chadwick and Liming Bu and Hongrun Yu and Yan Hu and Jon E. Wergedal and Subburaman Mohan and David J. Baylink},
  journal={Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society},
  year={2007},
  volume={15 2},
  pages={275-84}
}
MRL/Mpj mice are the only known strain of mouse that can regenerate cardiac lesions and completely heal ear punches without scarring. This study was undertaken to determine if MRL mice also have greater regrowth capabilities in amputated digit tips. Right paw digit tips of neonatal MRL mice were dissected, with the left front paws as uncut controls. Controls used for regrowth comparison were the DBA/2 and C57BL/6 inbred mouse strains. Consecutive x-ray images were captured of front paws at 0, 7… CONTINUE READING

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