Digit removal leads to discrepancies between the structural and functional organization of the forepaw barrel subfield in layer IV of rat primary somatosensory cortex

@article{McCandlish1996DigitRL,
  title={Digit removal leads to discrepancies between the structural and functional organization of the forepaw barrel subfield in layer IV of rat primary somatosensory cortex},
  author={Carl A. McCandlish and Cheng Xin Li and Robert S. Waters and Eugene M. Howard},
  journal={Experimental Brain Research},
  year={1996},
  volume={108},
  pages={417-426}
}
The physiological representation of the forepaw in rat primary somatosensory cortex (SI) is topographically organized. This representation is associated with the unique arrangement of barrels in layer IV of the forepaw barrel subfield (FBS) in SI and provides an example of a relationship between cortical structure and function. It has been reported that removal of peripheral afferent input to the FBS prior to postnatal day 5 or 6 results in a disorganized FBS, while deafferentation at later… CONTINUE READING