Diffusion-weighted imaging in patients with progressive multifocal leukoencephalopathy

  title={Diffusion-weighted imaging in patients with progressive multifocal leukoencephalopathy},
  author={Mirco Cosottini and Claudia Tavarelli and L. Del Bono and Grazia Doria and Marco Giannelli and Sara De Cori and Maria Chiara Michelassi and Carlo Bartolozzi and L. Murri},
  journal={European Radiology},
Progressive multifocal leukoencephalopathy (PML) is a severe demyelinating disease of the central nervous system due to JC polyoma virus infection of oligodendrocytes. PML develops in patients with impaired T-cell function as occurs in HIV, malignancy or immunosuppressive drugs users. Until now no imaging methods have been reported to correlate with clinical status. Diffusion-weighted imaging (DWI) is a robust MRI tool in investigating white matter architecture and diseases. The aim of our work… CONTINUE READING