Diffusion tensor microscopy indicates the cytoarchitectural basis for diffusion anisotropy in the human hippocampus.

@article{Shepherd2007DiffusionTM,
  title={Diffusion tensor microscopy indicates the cytoarchitectural basis for diffusion anisotropy in the human hippocampus.},
  author={Timothy M. Shepherd and Evren Ozarslan and Anthony T. Yachnis and Michael A. King and Stephen J. Blackband},
  journal={AJNR. American journal of neuroradiology},
  year={2007},
  volume={28 5},
  pages={958-64}
}
BACKGROUND AND PURPOSE Observing changes to water diffusivity and fractional anisotropy (FA) for particular hippocampal regions may improve the sensitivity and specificity of diffusion tensor MR imaging for hippocampal pathologies like Alzheimer disease and mesial temporal sclerosis. As a first step toward this goal, this study characterized the cytoarchitectural features underlying diffusion anisotropy in human hippocampus autopsy specimens at 60-microm in-plane resolution. MATERIALS AND… CONTINUE READING