Diffusion tensor imaging of white matter after cranial radiation in children for medulloblastoma: correlation with IQ.

@article{Mabbott2006DiffusionTI,
  title={Diffusion tensor imaging of white matter after cranial radiation in children for medulloblastoma: correlation with IQ.},
  author={D. Mabbott and M. Noseworthy and E. Bouffet and C. Rockel and S. Laughlin},
  journal={Neuro-oncology},
  year={2006},
  volume={8 3},
  pages={
          244-52
        }
}
  • D. Mabbott, M. Noseworthy, +2 authors S. Laughlin
  • Published 2006
  • Medicine
  • Neuro-oncology
  • Treatment of children with cranial-spinal radiation (CSR) for brain tumors is associated with adverse intellectual outcome and white matter damage. However, the correlation between IQ and measures of white matter integrity has received little attention. We examined apparent diffusion coefficient (ADC), fractional anisotropy (FA), and intelligence in pediatric patients treated with CSR for medulloblastoma relative to control subjects. ADC and FA measures were obtained for eight patients and… CONTINUE READING
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    References

    SHOWING 1-10 OF 39 REFERENCES
    White matter anisotropy in post-treatment childhood cancer survivors: preliminary evidence of association with neurocognitive function.
    • 164
    • PDF
    Subtle white matter volume differences in children treated for medulloblastoma with conventional or reduced dose craniospinal irradiation.
    • 123
    • Highly Influential
    Risks of young age for selected neurocognitive deficits in medulloblastoma are associated with white matter loss.
    • R. Mulhern, S. Palmer, +5 authors A. Gajjar
    • Medicine
    • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
    • 2001
    • 279
    Change in neurocognitive functioning after treatment with cranial radiation in childhood.
    • 356
    Abnormal hippocampal development in children with medulloblastoma treated with risk-adapted irradiation.
    • 79
    • PDF
    Attentional functioning and white matter integrity among survivors of malignant brain tumors of childhood.
    • 96