Diffusion tensor imaging of white matter after cranial radiation in children for medulloblastoma: correlation with IQ.

  title={Diffusion tensor imaging of white matter after cranial radiation in children for medulloblastoma: correlation with IQ.},
  author={D. Mabbott and M. Noseworthy and E. Bouffet and C. Rockel and S. Laughlin},
  volume={8 3},
  • D. Mabbott, M. Noseworthy, +2 authors S. Laughlin
  • Published 2006
  • Medicine
  • Neuro-oncology
  • Treatment of children with cranial-spinal radiation (CSR) for brain tumors is associated with adverse intellectual outcome and white matter damage. However, the correlation between IQ and measures of white matter integrity has received little attention. We examined apparent diffusion coefficient (ADC), fractional anisotropy (FA), and intelligence in pediatric patients treated with CSR for medulloblastoma relative to control subjects. ADC and FA measures were obtained for eight patients and… CONTINUE READING
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