Diffusion tensor imaging in the diagnosis of primary lateral sclerosis.

  title={Diffusion tensor imaging in the diagnosis of primary lateral sclerosis.},
  author={Aziz M. Ulug and Thomas Gr{\"u}newald and Michael T. Lin and Ayeesha Kamral Kamal and C G Filippi and R D Zimmerman and Myron Flint Beal},
  journal={Journal of magnetic resonance imaging : JMRI},
  volume={19 1},
PURPOSE To evaluate the utility of MR diffusion tensor imaging in diagnosing primary lateral sclerosis (PLS). MATERIALS AND METHODS Five patients who met clinical criteria for a diagnosis of PLS, and two patients with possible PLS of less than three years duration and eight normal volunteers were studied using MR diffusion tensor imaging. RESULTS All seven patients showed decreased diffusion anisotropy and increased diffusion constant in the PLIC, with complete separation from a normal… CONTINUE READING

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