Diffusion tensor imaging in schizophrenia: relationship to symptoms.

  title={Diffusion tensor imaging in schizophrenia: relationship to symptoms.},
  author={Laurie R. Skelly and Vince Calhoun and Shashwath A. Meda and Jinsuh Kim and Daniel H. Mathalon and Godfrey D. Pearlson},
  journal={Schizophrenia research},
  volume={98 1-3},
In this diffusion tensor imaging (DTI) study, the authors investigated white matter integrity in schizophrenia and the relationships between white matter alterations and specific symptoms of the disorder. We compared DTI images of 25 schizophrenia patients and 25 matched healthy controls and performed voxel-wise correlational analyses using the patient's DTI data and their severity scores of positive and negative symptoms. We found diffuse deficits in multiple types of white matter tracts in… CONTINUE READING