Diffusion tensor images in children with early-treated, chronic, malignant phenylketonuric: correlation with intelligence assessment.

@article{Peng2004DiffusionTI,
  title={Diffusion tensor images in children with early-treated, chronic, malignant phenylketonuric: correlation with intelligence assessment.},
  author={Steven Shinn-forng Peng and W Y I Tseng and Yin-Hsiu Chien and Wuh-Liang Hwu and Hon-Man Liu},
  journal={AJNR. American journal of neuroradiology},
  year={2004},
  volume={25 9},
  pages={1569-74}
}
BACKGROUND AND PURPOSE Diffusion tensor (DT) images can provide information about the nature of white matter changes, including axonal loss and demyelination. We applied DT imaging to verify white matter changes in patients with malignant phenylketonuria (PKU) and to correlate the findings with clinical intelligence quotients (IQs). METHODS We compared DT images with T2-weighted images in 12 patients with early-treated, chronic, stable malignant PKU and 12 age-matched control subjects. DT… CONTINUE READING
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