Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers

  title={Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers},
  author={Van J. Wedeen and R. P. Wang and Jeremy D. Schmahmann and Thomas Benner and W Y I Tseng and Guangping Dai and D. N. Pandya and Patric Hagmann and Helen D'Arceuil and Alex J. de Crespigny},
MRI tractography is the mapping of neural fiber pathways based on diffusion MRI of tissue diffusion anisotropy. Tractography based on diffusion tensor imaging (DTI) cannot directly image multiple fiber orientations within a single voxel. To address this limitation, diffusion spectrum MRI (DSI) and related methods were developed to image complex distributions of intravoxel fiber orientation. Here we demonstrate that tractography based on DSI has the capacity to image crossing fibers in neural… CONTINUE READING
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