Diffusion of water in tissues and MRI.

  title={Diffusion of water in tissues and MRI.},
  author={C F Hazlewood and H E Rorschach and C Lin},
  journal={Magnetic resonance in medicine},
  volume={19 2},
The purpose of this paper is to present an overview of the diffusive behavior of water in biological tissues. The analysis shows that obstructive barriers would have to occupy very large volume fractions in order to account for the reduction in the diffusion coefficient (D) observed in biological systems. Generally, most models lead to the supposition that a substantial fraction (20-40%) of the cell water is hydration water, or that the diffusion coefficient of the cytoplasmic water is reduced… CONTINUE READING