Diffusion modifies the connectivity of kinetic schemes for multisite binding and catalysis.

@article{Gopich2013DiffusionMT,
  title={Diffusion modifies the connectivity of kinetic schemes for multisite binding and catalysis.},
  author={Irina V Gopich and Attila Szabo},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2013},
  volume={110 49},
  pages={19784-9}
}
The simplest way to describe the influence of the relative diffusion of the reactants on the time course of bimolecular reactions is to modify or renormalize the phenomenological rate constants that enter into the rate equations of conventional chemical kinetics. However, for macromolecules with multiple inequivalent reactive sites, this is no longer sufficient, even in the low concentration limit. The physical reason is that an enzyme (or a ligand) that has just modified (or dissociated from… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

References

Publications referenced by this paper.
Showing 1-10 of 20 references

Similar Papers

Loading similar papers…