Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics.

Abstract

One of the main functions of the skin is to control the ingress and egress of water into and out of the body. The transport kinetics of water in the stratum corneum (SC), the dominant site of resistance in the skin, is normally described assuming a homogeneous membrane model. In the present work, the desorption of water from SC was studied and profiles… (More)
DOI: 10.1002/jps.21461

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