Diffusion kurtosis imaging predicts neoadjuvant chemotherapy responses within 4 days in advanced nasopharyngeal carcinoma patients.

@article{Chen2015DiffusionKI,
  title={Diffusion kurtosis imaging predicts neoadjuvant chemotherapy responses within 4 days in advanced nasopharyngeal carcinoma patients.},
  author={Yunbin Chen and Wang Ren and Dechun Zheng and Jing Xi Zhong and Xiangyi Liu and Qiuyuan Yue and Meng Liu and Youping Xiao and Weibo Chen and Queenie C. C. Chan and Jianji Pan},
  journal={Journal of magnetic resonance imaging : JMRI},
  year={2015},
  volume={42 5},
  pages={1354-61}
}
PURPOSE To explore the clinical value of diffusion kurtosis imaging (DKI) and monoexponential diffusion-weighted imaging (DWI) for predicting early response to neoadjuvant chemotherapy (NAC) in patients with nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS Fifty-nine patients with stage III-IVb NPC underwent four 3.0T MR scans: prior to, and on the 4th, 21st, 42nd days after NAC initiation. The parameters of DKI (corrected diffusion coefficient, D; excess diffusion kurtosis coefficient… CONTINUE READING
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