Diffusion in inhomogeneous media: theory and simulations applied to whole cell photobleach recovery.

@article{Siggia2000DiffusionII,
  title={Diffusion in inhomogeneous media: theory and simulations applied to whole cell photobleach recovery.},
  author={Eric D. Siggia and Jennifer Lippincott-Schwartz and Stefan Bekiranov},
  journal={Biophysical journal},
  year={2000},
  volume={79 4},
  pages={1761-70}
}
A continuum description for diffusion in a simple model for an inhomogeneous but isotropic media is derived and implemented numerically. The locally averaged density of diffusible marker is input from experiment to define the sample. Then a single additional parameter, the effective diffusion constant, permits the quantitative simulation of diffusive… CONTINUE READING