Diffusion dependent cell behavior in microenvironments.

  title={Diffusion dependent cell behavior in microenvironments.},
  author={Hongmei Yu and Ivar Meyvantsson and I. A. Shkel and David J. Beebe},
  journal={Lab on a chip},
  volume={5 10},
Understanding the interaction between soluble factors and cells in the cellular microenvironment is critical to understanding a wide range of diseases. Microchannel culture systems provide a tool for separating diffusion and convection based transport making possible controlled studies of the effects of soluble factors in the cellular microenvironment. In this paper we compare the proliferation kinetics of cells in traditional culture flasks to those in microfluidic channels, and explore the… CONTINUE READING
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Culture in microchannels enhances in vitro embryonic development of preimplantation mouse embryos

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