Diffusion Dynamics of Glycine Receptors Revealed by Single-Quantum Dot Tracking

  title={Diffusion Dynamics of Glycine Receptors Revealed by Single-Quantum Dot Tracking},
  author={M. Dahan and S. L{\'e}vi and C. Luccardini and P. Rostaing and B. Riveau and A. Triller},
  pages={442 - 445}
  • M. Dahan, S. Lévi, +3 authors A. Triller
  • Published 2003
  • Medicine, Chemistry
  • Science
  • Semiconductor quantum dots (QDs) are nanometer-sized fluorescent probes suitable for advanced biological imaging. We used QDs to track individual glycine receptors (GlyRs) and analyze their lateral dynamics in the neuronal membrane of living cells for periods ranging from milliseconds to minutes. We characterized multiple diffusion domains in relation to the synaptic, perisynaptic, or extrasynaptic GlyR localization. The entry of GlyRs into the synapse by diffusion was observed and further… CONTINUE READING
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