Diffusion Dynamics of Glycine Receptors Revealed by Single-Quantum Dot Tracking

@article{Dahan2003DiffusionDO,
  title={Diffusion Dynamics of Glycine Receptors Revealed by Single-Quantum Dot Tracking},
  author={Maxime Dahan and Sabine L{\'e}vi and Camilla Luccardini and Philippe Rostaing and B{\'e}atrice Riveau and Antoine Triller},
  journal={Science},
  year={2003},
  volume={302},
  pages={442 - 445}
}
Semiconductor quantum dots (QDs) are nanometer-sized fluorescent probes suitable for advanced biological imaging. We used QDs to track individual glycine receptors (GlyRs) and analyze their lateral dynamics in the neuronal membrane of living cells for periods ranging from milliseconds to minutes. We characterized multiple diffusion domains in relation to the synaptic, perisynaptic, or extrasynaptic GlyR localization. The entry of GlyRs into the synapse by diffusion was observed and further… 
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