Diffusible component from the spore surface of the fungus Aspergillus fumigatus which inhibits the macrophage oxidative burst is distinct from gliotoxin and other hyphal toxins.

@article{Mitchell1997DiffusibleCF,
  title={Diffusible component from the spore surface of the fungus Aspergillus fumigatus which inhibits the macrophage oxidative burst is distinct from gliotoxin and other hyphal toxins.},
  author={C. Mitchell and J. Slight and K. Donaldson},
  journal={Thorax},
  year={1997},
  volume={52 9},
  pages={
          796-801
        }
}
  • C. Mitchell, J. Slight, K. Donaldson
  • Published 1997
  • Biology, Medicine
  • Thorax
  • BACKGROUND The fungus Aspergillus fumigatus, whose spores are present ubiquitously in the air, causes a range of diseases in the human lung. A small molecular weight (< 10 kD) heat stable toxin released from the spores of clinical and environmental isolates of A fumigatus within minutes of deposition in aqueous solution has previously been described. A key effect of the toxin was to inhibit the oxidative burst of macrophages as measured by superoxide anion release. It was hypothesised that the… CONTINUE READING
    55 Citations
    Inhibition of neutrophil function following exposure to the Aspergillus fumigatus toxin fumagillin.
    • 44
    • Highly Influenced
    • PDF
    Trypacidin, a Spore-Borne Toxin from Aspergillus fumigatus, Is Cytotoxic to Lung Cells
    • 67
    • PDF
    Culture supernatants of patient-derived Aspergillus isolates have toxic and lytic activity towards neurons and glial cells.
    • 15
    • PDF
    Genes and molecules involved in Aspergillus fumigatus virulence.
    • 232
    Immunosuppressive substances in Aspergillus fumigatus culture filtrate
    • A. Watanabe, K. Kamei, +4 authors T. Kuriyama
    • Biology, Medicine
    • Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
    • 2003
    • 48

    References

    SHOWING 1-10 OF 38 REFERENCES
    Inhibition of phagocyte migration and spreading by spore diffusates of Aspergillus fumigatus.
    • 31
    Separation of mycotoxin-containing sources in grain dust and determination of their mycotoxin potential.
    • 45
    • PDF