Diffuse perineuronal nets and modified pyramidal cells immunoreactive for glutamate and the GABA(A) receptor alpha1 subunit form a unique entity in rat cerebral cortex.

@article{Wegner2003DiffusePN,
  title={Diffuse perineuronal nets and modified pyramidal cells immunoreactive for glutamate and the GABA(A) receptor alpha1 subunit form a unique entity in rat cerebral cortex.},
  author={Florian Wegner and Wolfgang H{\"a}rtig and Andreas Bringmann and J. Grosche and Kai Wohlfarth and Werner Zuschratter and G. E. Brueckner},
  journal={Experimental neurology},
  year={2003},
  volume={184 2},
  pages={705-14}
}
Perineuronal nets (PNs) consisting of polyanionic chondroitin sulfate proteoglycans (CSPG) and other extracellular matrix components create an exceptional microenvironment around certain types of neurons. In rat neocortex, three types of PNs can be distinguished after staining with Wisteria floribunda agglutinin (WFA) by their different morphological structure: lattice-like PNs associated with subpopulations of nonpyramidal neurons, weakly labeled PNs showing a pyramidal morphology, and diffuse… CONTINUE READING

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